Scientific publications
SAAP Family
1. The antimicrobial peptide SAAP-148 combats drug-resistant bacteria and biofilms.
De Breij A, Riool M, Cordfunke RA, Malanovic N, de Boer L, Koning RI, Ravensbergen E, Franken M, van der Heijde T, Boekema BK, Kwakman PHS, Kamp N, El Ghalbzouri A, Lohner K, Zaat SAJ, Drijfhout JW, Nibbering PH.
Sci Transl Med. 2018 Jan 10;10(423):eaan4044. doi: 10.1126/scitranslmed.aan4044.
PMID: 29321257
2. Potential factors contributing to the poor antimicrobial efficacy of SAAP-148 in a rat wound infection model.
Dijksteel GS, Ulrich MMW, Vlig M, Nibbering PH, Cordfunke RA, Drijfhout JW, Middelkoop E, Boekema BKHL.
Ann Clin Microbiol Antimicrob. 2019 Dec 3;18(1):38. doi: 10.1186/s12941-019-0336-7.
PMID: 31796055 (Free PMC article).
3. Design of Antimicrobial Peptides: Progress Made with Human Cathelicidin LL-37.
Wang G, Narayana JL, Mishra B, Zhang Y, Wang F, Wang C, Zarena D, Lushnikova T, Wang X.
Adv Exp Med Biol. 2019;1117:215-240. doi: 10.1007/978-981-13-3588-4_12.
PMID: 30980360 Review.
4. Synergistic microbicidal effect of cationic antimicrobial peptides and teicoplanin against planktonic and biofilm-encased Staphylococcus aureus.
Koppen BC, Mulder PPG, de Boer L, Riool M, Drijfhout JW, Zaat SAJ.
Int J Antimicrob Agents. 2019 Feb;53(2):143-151. doi: 10.1016/j.ijantimicag.2018.10.002. Epub 2018 Oct 10.
PMID: 30315918
P10 family
1. Eradication of meticillin-resistant Staphylococcus aureus from human skin by the novel LL-37-derived peptide P10 in four pharmaceutical ointments.
Nibbering PH, Göblyös A, Adriaans AE, Cordfunke RA, Ravensbergen B, Rietveld MH, Zwart S, Commandeur S, van Leeuwen R, Haisma EM, Schimmel KJM, den Hartigh J, Drijfhout JW, Ghalbzouri AE.
Int J Antimicrob Agents. 2019 Nov;54(5):610-618. doi: 10.1016/j.ijantimicag.2019.07.014. Epub 2019 Jul 26.
PMID: 31356860
2. Synergistic effect of two antimicrobial peptides, Nisin and P10 with conventional antibiotics against extensively drug-resistant Acinetobacter baumannii and colistin-resistant Pseudomonas aeruginosa isolates.
Jahangiri A, Neshani A, Mirhosseini SA, Ghazvini K, Zare H, Sedighian H.
Microb Pathog. 2020 Dec 17:104700. doi: 10.1016/j.micpath.2020.104700. Online ahead of print.
PMID: 33346078
3. LL-37-derived peptides eradicate multidrug-resistant Staphylococcus aureus from thermally wounded human skin equivalents.
Haisma EM, de Breij A, Chan H, van Dissel JT, Drijfhout JW, Hiemstra PS, El Ghalbzouri A, Nibbering PH.
Antimicrob Agents Chemother. 2014 Aug;58(8):4411-9. doi: 10.1128/AAC.02554-14. Epub 2014 May 19.
PMID: 24841266 Free PMC article.